Use Case Guide

Peptides for Anti-Aging

Longevity-focused peptides targeting cellular health, skin rejuvenation, and age-related decline.

Last updated: January 202610 min read

Peptides for Anti-Aging

How Anti-Aging Peptides Work

Anti-aging peptides target various mechanisms of aging, from telomere maintenance to cellular energy production. While longevity research is promising, most anti-aging peptides lack robust human clinical trial data proving they extend lifespan or healthspan.

Mechanism of Action

Different anti-aging peptides work through distinct mechanisms. Epitalon may activate telomerase to maintain telomere length. GHK-Cu modulates gene expression toward more youthful patterns. Thymic peptides support immune function that typically declines with age.

Important Considerations

Before You Start

  • Most anti-aging claims are based on limited research
  • Epitalon and injectable GHK-Cu are Category 2 restricted
  • Topical GHK-Cu remains available for skin applications
  • NAD+ boosters are available as supplements but peptides are restricted

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Frequently Asked Questions

Do anti-aging peptides actually work?

Evidence is mixed. Some peptides show promising results in cell culture and animal studies, but robust human clinical trials proving lifespan extension don't exist. GHK-Cu has the most evidence for skin-specific benefits.

What is Epitalon and is it available?

Epitalon is a synthetic tetrapeptide studied for telomerase activation. It was placed on FDA Category 2 in 2023, making it unavailable through compounding pharmacies. Research vendors still sell it, but quality and legality concerns apply.

Is GHK-Cu effective for anti-aging?

GHK-Cu has substantial evidence for skin benefits: promoting collagen synthesis, wound healing, and potentially reversing some age-related gene expression changes. Topical GHK-Cu remains available and is the most evidence-backed option for skin aging.

How do I choose an anti-aging peptide protocol?

Start with the most evidence-backed options: topical GHK-Cu for skin, lifestyle factors (exercise, sleep, nutrition) for systemic aging. Injectable anti-aging peptides have limited evidence and face regulatory restrictions.

Are there risks to anti-aging peptides?

Beyond standard quality concerns with unregulated products, theoretical risks include unknown effects of telomerase activation on cancer cells and long-term consequences of modulating aging pathways. No long-term human safety data exists.

What legal anti-aging peptide options exist?

Topical GHK-Cu products remain legal and available. NAD+ precursors like NMN and NR are sold as supplements. For injectable peptides, options are very limited since most are Category 2 restricted. Focus on lifestyle interventions with proven benefits.

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This website is for informational purposes only and does not constitute medical advice. Consult a licensed physician before using any peptides. Provider listings do not constitute endorsements. None of the statements on this site have been evaluated by the FDA.